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Americas vaccine requirements by country

The Americas split in two. The US, Canada and most Caribbean islands need little beyond routine vaccines. Large parts of South and Central America call for yellow fever protection, hepatitis A and typhoid, and care with mosquitoes. Here's what each country asks for, and what doctors recommend.

countries covered
28
have yellow fever risk areas where the vaccine is advised
10
have malaria risk in some or all areas
14
are malaria-free
14

General guidance, not medical advice. Entry rules change and depend on your route, health and nationality. Check the destination's embassy and see a travel health clinic 6 to 8 weeks before you go. Last checked September 2026.

The quick answer

Where do you need a yellow fever vaccine in the Americas?

No country here asks every traveller for a yellow fever certificate, but the vaccine is recommended for large parts of South America and eastern Panama. The CDC widened its map in 2026, adding parts of central Colombia, Bolivia and Peru, including Machu Picchu.

Vaccine recommended

10 countries have risk areas

You don't need proof to enter if you fly in from Europe or North America, but the vaccine protects you in the Amazon and other risk areas. Get it at least 10 days before you go.

Entry certificates

When you need the yellow card

Many countries ask for it if you arrive from a country with yellow fever risk, such as Brazil, Colombia or Peru, so moving between countries in the region can trigger the rule. French Guiana requires it from every traveller. These countries have no yellow fever risk areas of their own:

What to get

The vaccines that matter most for the Americas

Four things come up on most trips south of the US border. See the vaccine field guide for doses and timing.

Yellow fever

Recommended for risk areas

No country here asks every traveller for it, but the vaccine is recommended for most of Brazil and Paraguay and for risk areas of Peru, Colombia, Bolivia, Ecuador, Venezuela, Panama and Argentina. The CDC widened its map in 2026, including Machu Picchu. Get it at least 10 days before you go.

Hepatitis A and typhoid

Recommended for Latin America

Advised for Mexico, Central and South America and much of the Caribbean, especially if you'll eat street food or travel outside resorts. The US and Canada need routine vaccines only, but measles outbreaks since 2025 mean your MMR should be complete.

Malaria

Mostly rural, often not needed

14 of 28 countries have some risk, mostly in the Amazon, rural Central America and Haiti. Argentina, Paraguay, El Salvador and Belize are certified malaria-free, and big cities like Rio, Lima, Bogotá and Mexico City have no risk.

Dengue, Oropouche and Zika

Avoid mosquito bites

Dengue reached record levels across the Americas in 2024, and Oropouche has spread to Cuba, Brazil and Peru. There are no routine travel vaccines for them, so use repellent and cover up. If you're pregnant, talk to a doctor before visiting affected areas.

All 28 countries

Americas vaccine requirements by country

Open a country for its entry rules, recommended vaccines and malaria risk. Use the filters to narrow the list.

Showing 28 of 28

A

Antigua & Barbuda

Yellow fever: if from a risk countryNo malaria
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
Also consider
  • Typhoid, for longer stays

Malaria: No malaria.

Rules change. Check with the embassy and a travel clinic before you go.Antigua & Barbuda travel guide

Argentina

Yellow fever: vaccine advisedNo malaria
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Yellow fever vaccineRecommended for the Iguazú Falls area (Misiones) and parts of Corrientes; may be considered for some other northern provinces
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies, for rural areas

Malaria: Certified malaria-free by the WHO in 2019.

Rules change. Check with the embassy and a travel clinic before you go.Argentina travel guide

B

Bahamas

Yellow fever: if from a risk countryNo malaria
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
Also consider
  • Typhoid, for longer stays

Malaria: No regular malaria transmission.

Rules change. Check with the embassy and a travel clinic before you go.Bahamas travel guide

Barbados

Yellow fever: if from a risk countryNo malaria
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
Also consider
  • Typhoid, for longer stays

Malaria: No malaria.

Rules change. Check with the embassy and a travel clinic before you go.Barbados travel guide

Belize

Yellow fever: if from a risk countryNo malaria
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Certified malaria-free by the WHO in 2023.

Rules change. Check with the embassy and a travel clinic before you go.Belize travel guide

Bolivia

Yellow fever: vaccine advisedMalaria: some areas
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Yellow fever vaccineRecommended for areas east of the Andes below 2,300 m, including the Amazon and Santa Cruz department; not needed for La Paz or the Uyuni area
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Risk below 2,500 m, mainly in the Amazon departments of Beni and Pando. None in La Paz, Sucre, Potosí or the Uyuni salt flats.

Rules change. Check with the embassy and a travel clinic before you go.Bolivia travel guide

Brazil

Yellow fever: vaccine advisedMalaria: some areas
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Yellow fever vaccineRecommended for nearly all travellers, even on short trips, including Iguaçu Falls and the states of São Paulo and Rio de Janeiro
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Risk in the Amazon states, including Amazonas, Pará, Acre, Rondônia, Roraima and Amapá, and parts of Mato Grosso and Tocantins. None in Rio de Janeiro, São Paulo, Salvador, the coast or Iguaçu Falls.

Brazil doesn't require proof of yellow fever vaccination to enter, but some countries may ask for it at the airline counter when you fly onward from Brazil.

Rules change. Check with the embassy and a travel clinic before you go.Brazil travel guide

C

Canada

No entry vaccinesNo malaria
Required for entry
  • No vaccines required for entry
Recommended
  • Routine vaccines only
Also consider
  • Nothing extra beyond routine vaccines

Malaria: No malaria.

Canada has had a large measles outbreak since 2025. Make sure your MMR vaccination is complete.

Rules change. Check with the embassy and a travel clinic before you go.Canada travel guide

Chile

Yellow fever: if from a risk countryNo malaria
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies, for rural areas

Malaria: No malaria and no yellow fever risk, including Easter Island and Patagonia.

Rules change. Check with the embassy and a travel clinic before you go.Chile travel guide

Colombia

Yellow fever: vaccine advisedMalaria: some areas
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Yellow fever vaccineRecommended for most areas below 2,300 m, including the Amazon and Tolima; may be considered for Cartagena, Barranquilla, Cali and Medellín; not needed for Bogotá
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Risk in rural areas below 1,700 m, especially the Pacific coast (Chocó), the Amazon and Urabá. None in Bogotá, Medellín, Cartagena or the Coffee Region.

Yellow fever cases have risen in Tolima and nearby areas. The CDC advises a booster for some travellers vaccinated more than 10 years ago who are heading to higher-risk areas. Some national parks have asked visitors for proof of vaccination, so carry your yellow card.

Rules change. Check with the embassy and a travel clinic before you go.Colombia travel guide

Costa Rica

Yellow fever: if from a risk countryMalaria: some areas
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Very low risk, limited to a few rural areas of Limón province. Most travellers only need protection against bites.

Rules change. Check with the embassy and a travel clinic before you go.Costa Rica travel guide

Cuba

Yellow fever: if from a risk countryNo malaria
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Nothing extra beyond routine vaccines

Malaria: No malaria.

Oropouche and dengue have circulated widely since 2024. There's no vaccine for either, so use repellent and cover up, especially if you're pregnant.

Rules change. Check with the embassy and a travel clinic before you go.Cuba travel guide

D

Dominican Republic

Yellow fever: if from a risk countryMalaria: some areas
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Low risk, mainly in provinces near the Haitian border. Very low in Punta Cana and other resort areas.

Rules change. Check with the embassy and a travel clinic before you go.Dominican Republic travel guide

E

Ecuador

Yellow fever: vaccine advisedMalaria: some areas
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Yellow fever vaccineRecommended for the Amazon provinces east of the Andes below 2,300 m; not needed for Quito, Guayaquil or the Galápagos
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Risk in the Amazon provinces and the northern Pacific coast (Esmeraldas). None in Quito, Guayaquil, Cuenca, the highlands or the Galápagos.

Rules change. Check with the embassy and a travel clinic before you go.Ecuador travel guide

El Salvador

Yellow fever: if from a risk countryNo malaria
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Certified malaria-free by the WHO in 2021.

Rules change. Check with the embassy and a travel clinic before you go.El Salvador travel guide

G

Guatemala

Yellow fever: if from a risk countryMalaria: some areas
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Low risk in rural areas below 1,500 m, mainly Escuintla and Alta Verapaz. None in Guatemala City, Antigua or around Lake Atitlán.

Rules change. Check with the embassy and a travel clinic before you go.Guatemala travel guide

H

Haiti

Yellow fever: if from a risk countryMalaria: high risk
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Cholera
  • Rabies

Malaria: Risk across the country, including Port-au-Prince.

A severe security and humanitarian crisis driven by gang violence. Most governments advise against all travel.

Rules change. Check with the embassy and a travel clinic before you go.Haiti travel guide

Honduras

Yellow fever: if from a risk countryMalaria: most areas
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Risk in many rural areas and on the Bay Islands, highest in La Mosquitia (Gracias a Dios). Lower in Tegucigalpa and San Pedro Sula.

Rules change. Check with the embassy and a travel clinic before you go.Honduras travel guide

J

Jamaica

Yellow fever: if from a risk countryNo malaria
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Nothing extra beyond routine vaccines

Malaria: No malaria.

Rules change. Check with the embassy and a travel clinic before you go.Jamaica travel guide

M

Mexico

No entry vaccinesMalaria: some areas
Required for entry
  • No vaccines required for entry
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Very low risk, limited to a few rural areas, mainly in Chiapas. None in Mexico City, Cancún, the Riviera Maya, Los Cabos or other tourist areas.

Mexico has had large measles outbreaks since 2025. Make sure your MMR vaccination is complete.

Rules change. Check with the embassy and a travel clinic before you go.Mexico travel guide

N

Nicaragua

Yellow fever: if from a risk countryMalaria: some areas
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Risk mainly on the Caribbean coast and in some northern areas. Low in Managua, Granada and León.

Rules change. Check with the embassy and a travel clinic before you go.Nicaragua travel guide

P

Panama

Yellow fever: vaccine advisedMalaria: some areas
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Yellow fever vaccineRecommended for areas east of the Canal Zone, including Darién and Guna Yala; not needed for Panama City or the Canal Zone
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Risk in Darién, Guna Yala (San Blas), Bocas del Toro and the Ngäbe-Buglé region. None in Panama City or the Canal Zone.

Rules change. Check with the embassy and a travel clinic before you go.Panama travel guide

Paraguay

Yellow fever: vaccine advisedNo malaria
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Yellow fever vaccineRecommended for all areas except Asunción
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Certified malaria-free by the WHO in 2018.

Rules change. Check with the embassy and a travel clinic before you go.Paraguay travel guide

Peru

Yellow fever: vaccine advisedMalaria: some areas
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Yellow fever vaccineRecommended for the Amazon and, under the CDC's 2026 guidance, newly for some central areas including Machu Picchu; not needed for Lima or the coast
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Risk in the Amazon below 2,000 m, including Iquitos and Puerto Maldonado. None in Lima, Cusco, Machu Picchu, Arequipa or Lake Titicaca.

Machu Picchu is now inside a yellow fever recommended area. There's still no malaria risk there.

Rules change. Check with the embassy and a travel clinic before you go.Peru travel guide

T

Trinidad & Tobago

Yellow fever: vaccine advisedNo malaria
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Yellow fever vaccineAdvised for time in forested areas of Trinidad; not needed for Tobago or cruise stops
  • Hepatitis A
  • Typhoid
Also consider
  • Nothing extra beyond routine vaccines

Malaria: No malaria.

Rules change. Check with the embassy and a travel clinic before you go.Trinidad & Tobago travel guide

U

United StatesUSA

No entry vaccinesNo malaria
Required for entry
  • No vaccines required for entry
Recommended
  • Routine vaccines only
Also consider
  • Nothing extra beyond routine vaccines

Malaria: No malaria.

The US has had large measles outbreaks since 2025. Make sure your MMR vaccination is complete.

Rules change. Check with the embassy and a travel clinic before you go.United States travel guide

Uruguay

Yellow fever: if from a risk countryNo malaria
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies, for rural areas

Malaria: No malaria and no yellow fever risk.

Rules change. Check with the embassy and a travel clinic before you go.Uruguay travel guide

V

Venezuela

Yellow fever: vaccine advisedMalaria: most areas
Required for entry
  • Yellow fever certificate only if you arrive from, or had a long transit in, a country with yellow fever risk
Recommended
  • Yellow fever vaccineRecommended for most areas, including Canaima and Angel Falls; not needed for Caracas or Valencia
  • Hepatitis A
  • Typhoid
Also consider
  • Rabies

Malaria: Risk in many rural areas, highest in Bolívar (including Canaima and Angel Falls) and Amazonas. Very low in Caracas.

A severe political and humanitarian crisis with shortages of medicines. Most governments advise against all but essential travel.

Rules change. Check with the embassy and a travel clinic before you go.Venezuela travel guide

Common questions

Americas travel vaccines: questions answered

Do I need a yellow fever vaccine for South America?

No country we cover asks every traveller for it, but the vaccine is recommended for most of Brazil and Paraguay and for risk areas in Peru, Colombia, Bolivia, Ecuador, Venezuela, Panama and Argentina. Several countries also ask for a certificate if you arrive from a country with yellow fever risk, which can apply when you travel between countries in the region. Chile and Uruguay have no yellow fever risk.

Do I need a yellow fever vaccine for Machu Picchu?

Under the CDC's 2026 guidance, yes: Machu Picchu falls in a newly recommended area. Peru doesn't require proof for entry if you fly in from a country without yellow fever risk, but the vaccine is recommended, especially if you'll also visit the Amazon. Get it at least 10 days before you go.

Do I need malaria tablets for the Americas?

Usually only for specific rural routes. Malaria risk is limited to parts of the Amazon, rural Central America and Haiti, and 14 of the countries we cover have no malaria at all, including Argentina, Chile, Cuba, Jamaica and Uruguay. Cities like Rio de Janeiro, Lima, Bogotá, Quito and Mexico City are malaria-free.

Do I need vaccines for the USA, Canada or Mexico?

No vaccines are required for entry. Make sure your routine vaccines are up to date, especially measles (MMR), because all three countries have had large measles outbreaks since 2025. For Mexico, hepatitis A and typhoid are also recommended.

Do I need any vaccines for the Caribbean?

No Caribbean country we cover requires vaccines from every traveller, but many ask for a yellow fever certificate if you arrive from a country with yellow fever risk, such as Brazil. Hepatitis A is recommended for most islands, and typhoid for Haiti, the Dominican Republic and longer stays elsewhere. Protect yourself against mosquito bites, because dengue is common.

Check the official word

Where this information comes from

Yellow fever entry rules follow the CDC Yellow Book's country list, alongside WHO and UK guidance. Use these to double-check anything important for your trip.

Last checked: September 2026.

Planning more than one region?

Every region page uses the same labels, so you can compare rules at a glance. Then read the full country guide for safety, visas, money and local tips.