The World Health Organization issued updated yellow fever vaccination guidance for Brazil effective July 15. Proof of vaccination is now required for entry into Amazonas, Acre, Roraima and nine additional states. The single-dose vaccine provides lifelong immunity for most travelers.
Brazil recorded 47 yellow fever cases in 2025, concentrated in the Amazon region. The Ministry of Health expanded its vaccination campaign to 18 million people in high-risk zones. International airports in Sao Paulo and Rio de Janeiro will enforce the new rule at immigration.
Previous WHO guidance only recommended vaccination without mandatory proof. Several neighboring countries including Peru and Colombia already require certificates. The Pan American Health Organization supports the stricter entry policy.
What this means for you
Obtain the yellow fever vaccine at least 10 days before travel and carry the official certificate. Check your destination state against the updated WHO list before booking. Verify requirements with your airline as some carriers now request proof at check-in.
Consult a travel clinic if you have contraindications such as egg allergies or immune disorders. Keep digital and paper copies of your vaccination record. Avoid rural areas in affected states if you cannot receive the vaccine.
Clear documentation will prevent entry delays and ensure smoother travel throughout Brazil's interior regions.